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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D22B
All Species:
20
Human Site:
S168
Identified Species:
40
UniProt:
Q9NU19
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NU19
NP_060242.2
505
59081
S168
I
P
L
V
A
R
I
S
D
Q
N
A
S
G
A
Chimpanzee
Pan troglodytes
XP_527375
505
59106
S168
I
P
L
V
A
R
I
S
D
Q
N
A
S
G
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538894
488
57073
L169
T
V
R
E
K
T
R
L
E
K
F
R
Q
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5A6
516
59344
S179
T
V
T
L
S
G
T
S
D
P
H
A
L
A
D
Rat
Rattus norvegicus
NP_001020230
505
59036
S168
I
P
L
V
A
R
I
S
D
Q
N
A
S
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509397
560
64265
P170
Q
N
A
S
G
A
P
P
M
T
V
R
E
K
T
Chicken
Gallus gallus
XP_419261
747
85990
S410
I
P
L
V
A
R
I
S
D
Q
N
A
S
G
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685523
523
60664
S186
I
P
L
V
A
R
I
S
D
Q
N
A
S
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650941
546
61493
P204
L
R
N
Y
P
G
R
P
Q
L
Q
K
I
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023165
495
56525
N168
R
L
R
R
L
F
S
N
G
K
S
S
G
K
N
Sea Urchin
Strong. purpuratus
XP_797601
498
57012
A170
S
N
K
Q
D
E
K
A
D
K
F
W
A
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08484
637
73271
E238
D
S
K
K
T
Q
L
E
I
E
N
E
R
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
95.4
N.A.
62.2
98.4
N.A.
79.6
63.3
N.A.
70.1
N.A.
43
N.A.
46.9
46.7
Protein Similarity:
100
100
N.A.
96
N.A.
76.7
99
N.A.
83.5
65.1
N.A.
81.6
N.A.
57.6
N.A.
62.1
65.5
P-Site Identity:
100
100
N.A.
0
N.A.
20
100
N.A.
0
100
N.A.
100
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
100
N.A.
13.3
N.A.
40
100
N.A.
0
100
N.A.
100
N.A.
13.3
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
42
9
0
9
0
0
0
50
9
9
42
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
0
0
0
59
0
0
0
0
9
9
% D
% Glu:
0
0
0
9
0
9
0
9
9
9
0
9
9
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
17
0
0
0
0
% F
% Gly:
0
0
0
0
9
17
0
0
9
0
0
0
9
42
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
42
0
0
0
0
0
42
0
9
0
0
0
9
0
0
% I
% Lys:
0
0
17
9
9
0
9
0
0
25
0
9
0
17
0
% K
% Leu:
9
9
42
9
9
0
9
9
0
9
0
0
9
9
17
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
17
9
0
0
0
0
9
0
0
50
0
0
0
9
% N
% Pro:
0
42
0
0
9
0
9
17
0
9
0
0
0
0
0
% P
% Gln:
9
0
0
9
0
9
0
0
9
42
9
0
9
0
0
% Q
% Arg:
9
9
17
9
0
42
17
0
0
0
0
17
9
0
0
% R
% Ser:
9
9
0
9
9
0
9
50
0
0
9
9
42
9
9
% S
% Thr:
17
0
9
0
9
9
9
0
0
9
0
0
0
0
9
% T
% Val:
0
17
0
42
0
0
0
0
0
0
9
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _